International Association for the Study of Pain«    IASP Press«

Paris, France, 1993
Progress in Pain Research and Management, Vol. 2
Editors: Gerald F. Gebhart, Donna L. Hammond, and Troels S. Jensen
1994, 949pp, hardbound, ISBN 0-931092-07-8. Price: $65.00 US [IASP members: $45.50 US] 
Special Price: $40.00
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Includes plenary papers presented at the Congress and selected free communication papers. Main session topics include: psychologic factors related to chronic pain; the nociceptor as a dynamic entity; central nervous system plasticity: implications for pain perception; neuropathic pain; opioids and analgesia; pharmacology of pain control; headache; central pain; nociceptive processing; pain and age. Special topics include: the pharmacology of pain: twenty-five years of hope, despair, and hope; death of pain: pain, suffering, and ethics; the World Health Organization program in cancer pain relief and palliative care; pain management: quality assurance and changing practice; and perspectives on management of back pain in primary care.

Table of Contents: Proceedings of the 7th World Congress on Pain

Part I - Introductory Remarks

Part II - Special Lectures

The Pharmacology of Pain: Twenty-five Years of Hope, Despair, and Hope, Jean-Marie Besson

Death of Pain: Pain, Suffering, and Ethics, Margaret A. Someville

The World Health Organization Program in Cancer Pain Relief and Palliative Care, Kathleen M. Foley

Pain Management: Quality Assurance and Changing Practice, Christine Miaskowski

Perspectives on Management of Back Pain in Primary Care, Michael Von Korff

Part III - Psychologic Factors Related to Chronic Pain

Basic Issues in the Psychobiology of Pain, Herta Flor and Niels Birbaumer

Pain Behaviors Concepts: Controversies, Current Status, and Future Directions, Francis J. Keefe and John Lefebvre

The Challenge of Preventing Chronic Musculoskeletal Pain, Steven J. Linton

Pain Threshold, Symptom Severity, Coping Strategies, and Pain Belief as Predictors of Health Care Seeking in Fibromyalgia Patients, Laurence A. Bradley et al.

Comparative Sensory Evaluation of Parietal Tissues in Painful and Nonpainful Areas in Fibromyalgia and Myofascial Pain Syndrome, Leonardo Vecchiet, et al.

Patient Explanatory Models for Temporomandibular Disorders, Donna L. Massoth, et al.;  

The Relationship Between Pain and Depression: A Longitudinal Study of Early Synovitis, Suzanne M. Skevington

Part IV - The Nociceptor as a Dynamic Entity

Silent and Active Nociceptors: Structure, Functions, and Clinical Implications, Robert F. Schmidt, et al.

Changes in the Functional Organization of the Dorsal Horn During Acute Myositis and Following Muscle Nerve Axotomy, G÷tz Beylich, et al.

Different Mechanisms (Receptor Subtypes and Second Messenger Actions) Implicated in PGE2-Induced Sensitization of the Responses to Bradykinin and to Heat of Polymodal Receptors, Takao Kumazawa, et al.

Nociceptor Dynamics in Humans, Erik Torebj÷rk

Interaction of Immune-Competent Cells and Nociceptors, Christoph Stein

Part V - Central Nervous System Plasticity: Implications for Pain Perception

Central Plastic Responses to Pain, William D. Willis, Jr.

Electromyographic and Trigeminal Brainstem Neuronal Changes Associated with Inflammatory Irritation of Superficial and Deep Craniofacial Tissues in Rats, James W. Hu, et al.

Receptor and Cellular Mechanisms Involved in Mustard Oil-Induced Activation of Dorsal Horn Neurons, Fiona E. Munro, et al.

Differential Effects of Skin Inflammation, Extrasynaptic Substance P, and Noxious Skin Heating on Rhythmicity, Synchrony, and Nonlinear Dynamics in Rat Spinal Dorsal Horn, JŘrgen SandkŘhler, et al.

Central Control of Peripheral Joint Inflammation and Heat Hyperalgesia, Kathleen A. Sluka, et al.

Anatomical and Pharmacological Evidence for a Contribution of Protein Kinase C to Persistent Nociception and Hyperalgesia after Noxious Chemical and Thermal Stimulation, Terence Coderre, et al.

Gene Delivery to Mouse Sensory Neurons Using Herpes Virus Vectors, Gudarz Davar, et al.

Glutaminergic Neurotransmission, Proto-Oncogenes, and Pain, Masaya Tohyama, et al.; C-fos Activation by Noxious Input of Spinal Neurons Projecting to the Nucleus of the Tractus Solitarius in the Rat, Deolinda Lima, et al

Part VI - Neuropathic Pain

Multiple Mechanisms of Neuropathic Pain: A Clinical Perspective, Howard L. Fields and Michael C. Rowbotham

Clinical Phenomenology and Mechanisms of Reflex Sympathetic Dystrophy: Emphasis on Edema, Helmut Blumberg

Pathophysiological Spectrum of Organic and Psychogenic Disorders in Neuropathic Pain Patients Fitting the Description of Causalgia or Reflex Sympathetic Dystrophy, JosÚ L. Ochoa, et al.

Animal Models of Neuropathic Pain, Gary J. Bennett; The Properties of Unmyelinated Nociceptive Afferents Change in a Painful Chronic Constriction Neuropathy, Martin Koltzenburg, et al

Part VII - Opioids and Analgesia

Where and How Do Opioids Act?, Anthony H. Dickenson

Endogenous Opioid Systems in the Modulation of Pain: Behavioral Studies in Rat Models of Persistent Hyperalgesia, ValÚrie Kayser

Combining Opioids with Other Drugs: Challenges in Clinical Trial Design, Mitchell B. Max

Nimodipine, a Calcium Channel Blocker, Enhances Opiate Analgesia in Patients with Cancer Pain Tolerant to Morphine, Rosa Santillßn, et al.

Opioid Tolerance and Responsiveness: Research Findings and Clinical Observations, Russell K. Portenoy

Paradoxical and Other Pain Uncontrolled by Morphine, John S. Morley, et al.

A Comparison of Kapanol (a New Sustained-Release Morphine Formulation), MST Continus, and Morphine Solution in Cancer Patients: Pharmacokinetic Aspects of Morphine and Morphine Metabolites, Geoffrey K. Gourlay, et al

Part VIII - Pharmacology of Pain Control

Effects of Intravenous Ketamine and Alfentanil on Hyperalgesia Induced by Intradermal Capsaicin, Karen M. Park, et al,

Dissociation of Analgesia and Anesthesia under Ketamine, Burkhart Bromm, et al.; Serotonergic Mechanisms of Pain Control, Franšois Cesselin, et al.

NSAIDs for Cancer Pain: Meta-analysis of Efficacy, Elon Eisenberg, et al.

Do Preemptive Treatments Provide Better Pain Control? Henry J. McQuay

Lamotrigine and Analogs: A New Treatment for Chronic Pain? Meire Nakamura-Craig and Rhonda Lesley Follenfant

Part IX - Headache

Pathophysiology of Human Vascular Headache, Jes Olesen

Drug Mechanisms in Acute Migraine, Michael A. Moskowitz

Part X - Central Pain

A Thalamic Concept of Neurogenic Pain, Daniel Jeanmonod, et al.

The Clinical Characteristics and Sensory Abnormalities of Patients with Central Pain Caused by Multiple Sclerosis, Anders Ísterberg, et al

Part XI - Nociceptive Processing

Parabrachial Projections to the Forebrain Rostral to the Amygdala Studied With the PHA-L Method in the Rat, Jean-Franšois Bernard, et al.

Morphology of Primary Somatosensory Cortical Neurons Responsive to Noxious Stimulation of the Trigeminal Regions, Rhyuji Sumino, et al.

Reduction in the Size of Tactile Hypesthesia and Allodynia Closely Associated with Pain Relief in Patients with Chronic Pain, Katsuyuki Moriwaki et al.

Sensory Descriptors from Touch to Pressure-Pain and Experimental Variables: A Psychophysiological Study in Humans on Pressure-Pain Threshold, Gilles J. Lavigne, et al.

The Somatotopic Organization of Nociceptor-Induced Vascular Response Pattern Reflects Central Nociceptive Processing in Humans, Walter Magerl, et al.

Similarity of Threshold Temperatures for First Pain Sensation, Laser-Evoked Potentials, and Nociceptor Activation, Rolf-Detlef Treede, et al

Part XII - Pain and Age

Pain, Affect, and Cognition in Children: 1. The Influence of Affective State on Pain in Children, Robert Johnson, et al.

Pain, Affect, and Cognition in Children: 2. Recall Bias Associated with Pain, Robert Johnson and Susan H. Spence

Factors Contributing to the Properties of the Cutaneous Withdrawal Reflex in Human Neonates, 
Katharine Andrews and Maria Fitzgerald

Comparison of Chronic Pain Experience Between Young and Elderly Patients, Trevor M. Corran, et al

The organization of this book is elegant and reflects not only the multitude of disciplines involved in chronic pain management but the various layers, or hierarchies, through and by which pain becomes embedded within the nervous system . . . It provides an excellent source for references and could encourage even the most reticent of practitioners to become excited about researches into chronic pain as a manifestation of nervous system response to injury... The Clinical Journal of Pain
When you open these pages, be prepared for a mind-blowing experience . . . The central theme of the Congress was plasticity of the nervous system in response to insult . . . These research papers reveal the constant plasticity of the sensation of pain . . . More than 2500 references (over 50% of which are dated from 1990 onward) are a rich resource for anyone wishing to research a particular field. Many articles have been updated to include referenced information from 1994 . . . This volume . . . should be available wherever the subject of pain is of some importance. Anaesthesia and Intensive Care
Overall, this volume reviews important developments of the neurobiology and pharmacology of pain, which await widespread clinical application. This is not found anywhere else under one cover . . . a valuable reference for all practising anaesthestists especially those involved in postoperative pain management [and it] deserves presence in the personal library of the full time clinician. Canadian Journal of Anaesthesia

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